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Is it anxiety — or something else?

Anxiety isn’t always in your head. We explore hormones, metabolism, and root causes before rushing to label or treat.

Updated over 3 months ago

If you’ve ever been told “it’s just anxiety” — but something inside you knew it was more — you were probably right.

At Fishtown Medicine, we take a step back and ask:

What else could be driving this?

Because anxiety is real — but it’s not always the root cause. Sometimes it’s a signal from deeper systems that need attention.


🧠 Symptoms that look like anxiety, but aren’t always:

  • Racing heart

  • Chest tightness

  • Shakiness or dizziness

  • Brain fog

  • Irritability or overwhelm

  • Trouble falling or staying asleep

  • Morning dread or mid-day crashes

These can be caused by emotional stress — or by hormones, blood sugar swings, nutrient imbalances, or nervous system dysregulation.


🧪 What we look for beyond mood:

1. Thyroid health

  • Overactive thyroid (hyperthyroidism or Hashimoto’s flares) can mimic anxiety

  • Underactive thyroid can create fatigue-driven anxiety or looping thoughts

We check:
TSH, Free T4, Free T3, Reverse T3, and thyroid antibodies


2. Blood sugar and insulin resistance

  • Crashes in blood sugar (reactive hypoglycemia) can cause panic-like symptoms

  • Rising insulin levels over time can lead to inflammation, irritability, fatigue

We check:
Fasting insulin, HOMA-IR, glucose curves, A1C, and nutrient response


3. Cortisol and circadian rhythm

  • High evening cortisol = wired but tired

  • Flat morning cortisol = dread, overwhelm, no get-up-and-go

  • Dysregulated rhythm often gets labeled as "generalized anxiety" — when it's hormonal

We may check:
AM cortisol, salivary panels, or symptoms over 24 hours


4. Perimenopause, PCOS, and low testosterone

  • Estrogen and progesterone imbalances can cause heart racing, insomnia, and mood swings

  • Low testosterone (in men or women) can present as anxiety, low motivation, or sensory overload

  • PCOS patients may experience cycles of anxious energy → crash


5. Nutrient deficiencies

  • Low B12, magnesium, iron, and omega-3s can affect mood and focus

  • MTHFR-related methylation issues can cause anxiety in response to stress or histamine


🩺 Our approach:

  • Validate your experience — anxiety is real, whether or not it’s the root

  • Zoom out before labeling — we don’t treat labs in isolation, and we don’t treat emotions as pathology

  • Layer in lifestyle, nervous system regulation, nutrition, and clinical testing

  • Only introduce meds or supplements when the system as a whole makes sense

We believe anxiety is not a diagnosis — it’s a signal. Our job is to decode it.


💡 Bottom line:

Anxiety isn’t always in your head.
Sometimes it’s in your thyroid, your gut, your glucose, or your trauma history.
We look at all of it — not to overcomplicate your care, but to get it right.

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